1968 Edmonton Eskimos
Edmonton compiled a record of 8-7-1, finishing third in West for the third straight year and would lose to the Calgary Stampeders in the Division Semifinal. The team was led by quarterback Frank Cosentino, who threw for 858 yards and Jim Thomas who 881 receiving yards to go along with 369 rushing yards. The defence created 57 turnovers, with John Wydareny recording seven interceptions.
Joseph B. Ryan is inducted into the Canadian Football Hall of Fame as a Builder.
| 1968 (20th season) |
| Record: 8-7-1 (3rd West) |
| Home: 4-3-1 | Away: 4-4-0 |
| Playoffs: 0-1 | Division Semifinal |
| Head coach: Neill Armstrong (5th season) |
| CFL All-Stars: John LaGrone |
| West All-Stars: John LaGrone |
| Hall of Fame: Joseph B. Ryan (Builder) |
| Major award winners: None |
| Date | Opponent | Result (record) |
| July 31 | at Montreal Alouettes | W 27-10 (1-0) |
| August 2 | at Toronto Argonauts | L 4-32 (1-1) |
| August 7 | vs. Saskatchewan Roughriders | T 10-10 (1-1-1) |
| August 15 | at BC Lions | W 18-17 (2-1-1) |
| August 20 | vs. BC Lions | L 12-4 (2-2-1) |
| August 28 | vs. Calgary Stampeders | L 12-7 (2-3-1) |
| September 2 | at Saskatchewan Roughriders | L 2-29 (2-4-1) |
| September 8 | at Calgary Stampeders | W 10-8 (3-4-1) |
| September 11 | vs. Ottawa Rough Riders | W 20-25 (4-4-1) |
| September 22 | at Winnipeg Blue Bombers | L 13-25 (4-5-1) |
| September 28 | vs. Hamilton Tiger-Cats | L 31-7 (4-6-1) |
| October 5 | vs. BC Lions | W 5-13 (5-6-1) |
| October 13 | at Winnipeg Blue Bombers | W 22-8 (6-6-1) |
| October 20 | vs. Calgary Stampeders | W 13-14 (7-6-1) |
| October 27 | vs. Winnipeg Blue Bombers | W 22-32 (8-6-1) |
| October 30 | at Saskatchewan Roughriders | L 20-34 (8-7-1) |
| November 10 | at Calgary Stampeders | L 13-29 Division Semifinal |